Pronamel Science: Helping Prevent Erosive Tooth Wear and Maintaining Enamel
Strengthen and protect with the unique formulation of Pronamel1-10
The unique formulation of Pronamel delivers minerals into the enamel to help strengthen and protect from tooth erosion7,11
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A unique optimised formulation that delivers superior fluoride uptake*1,2
Pronamel contains 1450ppm fluoride in an optimised formulation designed to maximise intraoral fluoride. By omitting components that inhibit fluoride uptake, which are present in many fluoride toothpastes, this unique Pronamel dual-protection formulation enhances remineralisation and inhibits demineralisation, strengthening and protecting enamel.1–4
Pronamel optimised formulation:
- No phosphates2,6,7
- No polyvalent metal ions7
- Ionic form of fluoride7
- No SLS8
- Neutral pH9
- Low abrasivity†10,12
SLS, sodium lauryl sulphate*Compared with tested, non-optimised fluoride toothpastes†Only Pronamel Daily Protection, Pronamel Extra Freshness and Pronamel For Children
Dual protection for stronger, more resilient enamel7,13
The unique Pronamel formulation actively improves mineral uptake and leaves enamel more resilient to subsequent acid challenges.7,13
In vitro SEM images of enamel cross-sections show variations in mineral density14SEM, scanning electron microscope
Not all fluoride toothpastes are the same5,15
How Pronamel protects against tooth erosion
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Sensodyne Pronamel maintains higher levels of fluoride
In an in situ study against a non-optimised fluoride toothpaste, the optimised Pronamel formulation maintained higher levels of fluoride in subjects’ saliva 1 hour after brushing.3
Adapted from GSK data on file RH02217, 20143
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Sensodyne Pronamel creates an environment in the mouth that supports fast remineralisation for the prevention of tooth erosion3
In an in situ study against a non-optimised fluoride toothpaste, the optimised Pronamel formulation1 maintained higher calcium bioavailability in subjects’ saliva.
Adapted from GSK data on file RH02217, 20143
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Sensodyne Pronamel enhances remineralisation by delivering up to 3 times more fluoride uptake into enamel in vitro†16
Up to 3X higher fluoride uptake† in vitro vs. a non-optimised, 1450ppm fluoride NaF toothpaste16
In laboratory studies, Pronamel delivered more fluoride, deeper into the enamel for superior remineralisation vs. a non-optimised fluoride toothpaste.†16
In vitro cross-sectional DSIMS images of enamel surfacesDSIMS, dynamic secondary ion mass spectrometry†Based on mean fluoride/oxygen ratio measured at a depth of 20μm; vs. a non-optimised fluoride toothpaste
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Sensodyne Pronamel improves mineral uptake, leaving enamel more resilient to subsequent acid challenge7
In an in situ study, Pronamel increased the surface microhardness of acid-softened enamel, leaving it stronger and more resilient to dietary acid challenges,7,17 with 25% greater surface microhardness recovery vs. a non-optimised fluoride toothpaste.7
Adapted from Barlow et al. 20097
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Sensodyne Pronamel locks in more minerals for superior inhibition of demineralization†18
5X greater protection from demineralisation*in vitro vs. a non-optimised, 1450ppm fluoride NaF toothpaste18
In laboratory studies, Pronamel inhibited demineralisation of enamel, locking in more minerals vs. a non-optimised fluoride toothpaste.*18
In vitro cross-sectional BSE-SEM images of enamel surface lesionsBSE-SEM, back-scattered electrons-scanning electron microscope
*In vitro. Based on mean overall mineral loss; vs. a non-optimised fluoride toothpaste
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A gentle formulation helps ensure minimal wear of acid-softened enamel10
Sensodyne Pronamel has a low abrasion formula, helping to maintain the structural integrity of the enamel surface.*10
In vitro SEM cross-sectional images of enamel surface structure
*Pronamel Daily Protection and Pronamel Extra Fresh only
Offer Pronamel as an effective way to prevent tooth erosion and maintain enamel strength
Sensodyne Pronamel Toothpaste
Pronamel products are designed to help protect against erosive tooth wear7,17,18–21
Pronamel products are designed to help protect against erosive tooth wear7,17,18-21
The Sensodyne Pronamel range
Find out how the Sensodyne Pronamel range can help your patients.
