Joint pain: Signs and symptoms

Woman holding wrist

Recognising mechanical joint pain including osteoarthritis

Mechanical joint pain, including osteoarthritis, can lead to significant physical1 and psychosocial2 impact for patients.

Here we review the signs and symptoms of mechanical joint pain to help you identify this disorder.

Woman holding knee

Signs and symptoms of mechanical joint pain

Mechanical joint pain, or activity related pain, most commonly affects the knees, hips and hands and includes osteoarthritis.3-6

Osteoarthritis is characterised by:3,6-8

  • Activity-related joint pain/stiffness
  • Morning joint stiffness or stiffness after activity that normally resolves in <30 minutes
  • Possible inflammation
  • Possible crepitus – a crackling, grating or crunching sound that occurs with joint movement
  • Impaired function

Knee pain most commonly develops slowly but can also have a sudden onset, and may be aggravated by climbing stairs or rising from a chair.8

  • According to NICE guidance,3 osteoarthritis can be diagnosed clinically without investigations if a person:

    • Is 45 or over and
    • Has activity related joint pain and
    • Has either no morning joint-related stiffness or morning stiffness that lasts no longer than 30 minutes

    To help inform the identification of osteoarthritis consider asking the following questions:9

    • When during the day do you experience joint pain and how long does it last?
    • How quickly has your joint pain or stiffness developed?
    • Do you have hot swollen joints?
    • Have you experienced any fever or unexplained weight loss?
    • Have you had a recent injury?
    • Do you have any other medical conditions?
  • Patients should be referred to a GP if they report:10

    • Stiffness lasting longer than 30 minutes
    • Rapid worsening of symptoms
    • If joints are hot or swollen
    • If there is fever and/or unexplained weight loss in addition to joint pain
    • If pain occurred immediately after trauma
    • If patients are suffering from joint pain and have previously been diagnosed with cancer
  • Whilst not necessary for initial diagnosis of osteoarthritis, plain radiography may be considered (in combination with clinical diagnostic criteria) for the diagnosis of atypical cases and/or morphological assessment.10-12

    Classical radiographical features of osteoarthritis include focal, non-uniform joint space narrowing; osteophytes; subchondral bone sclerosis and subchondral ‘cysts’. 10-12

    Plain radiography alone is not considered sufficient to make a diagnosis of osteoarthritis11 due to a poor correlation between disease symptoms and radiographic changes3 – particularly in early disease.12

Understanding joint pain and osteoarthritis

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Causes

Find out about the causes of joint pain and osteoarthritis.

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Management

Learn how joint pain and osteoarthritis can be managed.

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Helping pharmacy teams manage joint pain effectively

Access editorially independent articles and learning materials created by The Royal Pharmaceutical Society supported by a partnership with GSK.

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Voltarol 12 Hour Joint Pain Relief 2.32% Gel

Voltarol 12 Hour Joint Pain Relief 2.32% Gel

All day joint pain relief

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Voltarol Osteoarthritis Joint Pain Relief 1.16% Gel

Voltarol Osteoarthritis Joint Pain Relief 1.16% Gel

Proven to be as effective as ibuprofen tablets for localised joint pain.13

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Patient care resources

Access resources for your patients.

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