The science of caffeine and paracetamol
Paracetamol exerts its analgesic and antipyretic effect by inhibition of prostaglandins.1 Caffeine on other hand has an adjuvant action due to inhibition of :-inhibition of the transmission of pain signal.
-Stimulation of neuronal activity resulting in mood elevation and reduced pain sensation.
-Regulation of vascular tone.
Do you know that contrary to popular believe, caffeine is not considered an addictive compound?3
First discovered in 850 A.D., caffeine was extracted as an active compound in 1819. It is the most common legal psychoactive drug and is a chemical relative of theophylline (used in treatment of asthma).2,3 Known for some of its effects such as increasing metabolic activity and heart rate, alertness, wakefulness and concentration, it is now combined with analgesics to increase absorption from the stomach.2,3