Chlorphenamine formulations
Panadol Cold & Flu is specially formulated with chlorphenamine
Formulations with chlorphenamine provide effective relief from the runny nose and sneezing symptoms of the common cold and flu.1-3
Chlorphenamine is a potent antihistamine1
Chlorphenamine maleate is an antihistamine inverse agonist of H1 histamine receptors, providing relief from symptoms such as runny nose and sneezing.1-3 The effects of chlorphenamine have been reported to last from 3 to 6 hours.1
Chlorphenamine alleviates rhinorrhoea and sneezing associated with colds and flu4
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As an inverse histamine agonist, chlorphenamine competes with histamine for H1 receptor sites in the respiratory tract5
Relief of sneezing3-5
The antihistamine effect of chlorphenamine provides temporary relief from sneezing.3-5
Relief of rhinorrhoea1,3-5
Chlorphenamine provides effective temporary relief from a runny nose.1,3-5
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A double-blind, randomised study found chlorphenamine is significantly effective at reducing a runny nose and sneezing3
N=40 subjects with induced (rhinovirus type 39) colds were treated with chlorphenamine 4 mg, given every 4 hours (24 mg/day) for 5 days, or placebo, in a randomised, double-blind study.
Chlorphenamine 4 mg was found to significantly relieve the runny nose and sneezing symptoms of an experimentally acquired common cold, compared with placebo (p<0.0002).3
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Side Effects
Occurring at an unknown frequency, chlorphenamine may cause the following adverse reactions: anaphylaxis, angioedema, allergy, anorexia, confusion, excitation, irritability, nightmares, paradoxical excitation, hypotension, thickening of bronchial secretions, vomiting, abdominal pain, diarrhoea, dyspepsia, exfoliative dermatitis, rash, urticaria, photosensitivity, muscle twitching, muscle weakness, urinary retention, and chest tightness.
Common adverse events related to chlorphenamine include: sedation, somnolence, blurred vision, nausea, dry mouth, and fatigue.1
Very common: sedation somnolence.1
The benefits of Chlorphenamine, Panadol Cold & Flu
Panadol Cold & Flu
Panadol Cold & Flu decongests the nose with pseudoephedrine. In addition, this product also contains Paracetamol and Chorpheniramine Maleate for the relief of various cold and flu symptoms.
Panadol Cold & Flu – Your Cold & Flu Partner
The Panadol Cold & Flu range
Find out how the Panadol Cold & Flu range can help your patients.
