The science of Optizorb technology

Optizorb technology contains three main ingredients which are: alginic acid that draws fluid from the stomach into the tablet causing it to swell and break apart; calcium carbonate that works together with alginic acid to boost the disintegration of the tablet and, crospovidone which acts as a superdisintegrant due to its ability to dissolve well in water.1,2

Paracetamol disintegrating in the stomach

Basics of Optizorb technology

This is a revolutionary technology that helps speed the breakdown of paracetamol tablets in the stomach2 so that the drug is absorbed fast and pain relief can start as early as 15 minutes after paracetamol ingestion with 2 tablets (1000 mg dose).3

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The absorption of paracetamol occurs in the small intestine and as such is dependent on the rate of emptying of stomach contents into the small intestine. Optizorb technology increases the gastric emptying time of the drug.2

Discover the Calpol range with Optizorb technology

Calpol Tablets pack shot

Calpol Tablets with Optizorb technology

With a revolutionary dispersion and dissolution technology2 that speeds up absorption and starts relieving pain in just 15 minutes with 2 tablets (1000 mg dose),3 Calpol Tablets provides faster and efficient pain relief compared with standard paracetamol tablets.1,2

S0 CALPOL Tablets. Each tablet contains 500 mg Paracetamol. Reg no: 44/2.7/0321.

GlaxoSmithKline Consumer Healthcare South Africa (Pty) Ltd. 39 Hawkins Avenue, Epping Industria 1, Cape Town, 7460. Reg. No: 2014/173930/07. For full prescribing information refer to the professional information approved by the medicines regulatory authority. For any further information, including safety, please contact the GSK Hotline on +27 11 745 6001 or 0800118274.

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Man with a fever


Paracetamol is a well-known antipyretic. Learn more about fever and how to manage it.

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Paracetamol chemical structure

Paracetamol basics

Globally, paracetamol or acetaminophen is one of the most used analgesic and antipyretic over-the-counter drugs. Both its names are derived from its chemical name, which is N-acetyl-para-aminophenol.1

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Patient in consultation with a pharmacist

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