Panadol Overview

Happy child and mother

With a presence in over 80 countries, Panadol is one of the world’s most trusted pain relievers.1,2

Panadol with paracetamol

Paracetamol chemical structure

Paracetamol

Globally, paracetamol or acetaminophen is one of the most used analgesic and antipyretic over-the-counter drugs.3

Paracetamol + caffeine chemical structure

Multi-component paracetamol preparations

Paracetamol is currently formulated as a single compound or as an active ingredient of multi-component preparations in combination with active ingredients1 to provide relief from fever and different types of pain (e.g. muscular and joint pains, headaches and dysmenorrhoea).

Picture of a stomach

Can be taken on an empty stomach

Paracetamol does not compromise the stomach’s protective lining and can be taken even on an empty stomach or by those at risk of stomach ulcers.4,5*

Innovative technology

  • Optizorb technology

    Optizorb formulation icon

    Optizorb technology contains three main ingredients which are alginic acid, calcium carbonate and crospovidone that help speed the breakdown of paracetamol tablets in the stomach.6,7

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Product Information: Please consult the summary of product characteristics for full product information. Panadol 500mg Film Coated Tablets (paracetamol), Panadol Actifast Tablets 500mg (paracetamol), Panadol Extra 500mg/65mg Soluble Effervescent Tablets (paracetamol, caffeine), Panadol Night Tablets (paracetamol, diphenhydramine hydrochloride), Panadol Baby 120mg/5ml Oral Suspension (paracetamol). Indications 500mg Film Coated, Actifast & Extra Soluble Effervescent Tablets: Short-term management of headaches, musculoskeletal disorders, menstrual pains, toothache, symptoms of colds and flu. Night: Short-term treatment of bedtime symptoms of cold and flu pain, rheumatic and muscle pain, backache, toothache, headache, menstrual pain. Baby: Short term pain relief of teething, toothache and sore throats and for fever reduction associated with colds and flu and childhood infections. Dosage Minimum dosing interval between paracetamol containing products is 4 hours. The lowest dose necessary to achieve efficacy should be used. 500mg Film Coated Tablets: Adults and children 16 years and over: 1-2 tablets, every 4-6 hours, as required. Max 8 tablets in 24 hours.  Children aged 10-15 years of age: 1 tablet, every 4-6 hours as required.  Max 4 tablets in 24 hours. Do not give to children for more than 3 days without consulting a doctor. Do not give to children under 10 years. Actifast Tablets: Adults and children 16 years and over: 1-2 tablets every 4-6 hours as required. Max 8 tablets in 24 hours. Children aged 12-15 years: 1 tablet every 4-6 hours as required. Max 4 tablets in 24 hours. Do not give to children for more than 3 days without consulting a doctor. Do not give to children under 12 years. Extra Soluble Effervescent Tablets: Adults and children 16 years and over: 2 tablets up to 4 times a day. Do not exceed 8 tablets in 24 hours. You may need a lower dose if you are underweight (<50kg), malnourished, dehydrated or if you have alcohol problems. Children aged 12-15 years: 1 tablet up to 4 times a day. Do not exceed 4 tablets in 24 hours. Do not give to children under 12 years. Night: Adults and children 16 years and over: 2 tablets, 20 minutes before bed. Children aged 12-15 years: 1 tablet, 20 minutes before bed. Other products containing paracetamol may be taken during the day but the total daily dose of paracetamol must not exceed 4000mg for adults and 2000mg for children aged 12-15 years. Do not give to children under 12 years except on medical advice. Avoid use in elderly patients with confusion. Avoid use with other antihistamine-containing products. Do not use for more than 7 days without medical advice. Baby: Aged 2-3 months: Post vaccination fever and other causes of pain and fever only if weighs over 4 kg and born after 37 weeks: One 2.5 mL measure.  If necessary, after 4-6 hours, give a second 2.5 mL dose. Do not give to babies less than 2 months of age.  Do not give more than 2 doses.  Leave at least 4 hours between doses. If further doses are needed, talk to your doctor or pharmacist. 3-6 months: 2.5 mL per dose; 6-24 months: 5 mL per dose; 2-4 years: 7.5 mL per dose; 4-8 years: 10 mL per dose; 8-10 years: 15 mL per dose; 10-12 years: 20 mL per dose. Do not give more than 4 doses in any 24-hour period. Do not give this to your child for more than 3 days without speaking to your doctor or pharmacist. Contraindications All: Hypersensitivity to paracetamol or any of the other ingredients. Night: Closed angle glaucoma, porphyria. Precautions All: Do not use with any other paracetamol-containing products. The concomitant use with other products containing paracetamol may lead to an overdose. Paracetamol overdose may cause liver failure which can lead to liver transplant or death. Patients with depleted glutathione levels / glutathione depleted states, chronic alcoholism or sepsis. Underlying liver disease, liver or kidney impairment. Do not exceed the stated dose. Prolonged use except under medical supervision may be harmful. Actifast Tablets: Contains 352 mg sodium per 2 tablet dose. Extra Soluble Effervescent Tablets: Avoid excessive caffeine intake. Caution in those with hereditary sugar intolerance or on a low sodium diet. Should not be used in pregnancy or lactation without medical advice. Night: Avoid use with alcohol. Avoid concurrent use with sedatives (including hypnotics and anxiolytics), antimuscarinics and other antihistamines. Caution in those with epilepsy or seizure disorders, myasthenia gravis, narrow angle glaucoma, prostatic hypertrophy, urinary retention, asthma, bronchitis, COPD or with any form of glucose-galactose malabsorption or lactase deficiency. Avoid use of MAOIs within 2 weeks. Should not be used during pregnancy or lactation without medical advice. Side Effects All: Very rare cases of serious skin reactions have been reported. All very rare: Hypersensitivity reactions including anaphylaxis and skin rash, thrombocytopenia, angioedema, Stevens-Johnson syndrome, Toxic Epidermal Necrolysis, bronchospasm, hepatic dysfunction. Extra Soluble Effervescent Tablets: Frequency unknown: Nervousness, dizziness. When combined with dietary caffeine intake, higher doses of caffeine may increase potential for caffeine related adverse events such as insomnia, restlessness, anxiety, irritability, headaches, GI disturbances and palpitations. Night: Common: Fatigue, sedation, attention disturbance, dizziness, unsteadiness, dry mouth. Frequency unknown: confusion, paradoxical excitation, GI disturbances, convulsions, headache, paraesthesia, dyskinesias, blurred vision, tachycardia, palpitations, muscle twitching, urinary difficulty, urinary retention, thickening of bronchial secretions.Overdose: Immediate medical advice should be sought in the event of an overdose, even if symptoms of overdose are not present. Legal Category 500 mg Film Coated & Actifast Tablets: ≤12 Tablets GSL; ≤24 Tablets Pharmacy Only. Extra Soluble Effervescent Tablets & Night: Phamacy Only. Baby: 60 ml GSL; 100 ml Pharmacy Only. MA Number: 500 mg Film coated Tablets: PA 678/107/1; Actifast Tablets: PA 678/39/12; Extra Soluble Effervescent Tablets: PA 678/39/10; Night: PA 678/39/8; Baby: PA 678/39/3. MA Holder: GlaxoSmithKline Consumer Healthcare (Ireland) Limited, 12 Riverwalk, CityWest Business Campus, Dublin 24. Text prepared: June 2021. Further information available on request. Trade marks are owned by or licenced to the GSK group of companies. Contains Paracetamol. Always read the label/leaflet.

Panadol logo

The Panadol range includes products with innovative technology for faster disintegration and absorption5,8 and, in combination with other ingredients such as caffeine to effectively handle tough pains.9-14

Panadol offers a range of solutions for individual patient needs

Panadol pack shot

Panadol 500mg Film-coated Tablets (paracetamol)

Disintegrates faster and available for absorption quicker6† to provide pain relief.

Panadol Actifast pack shot

Panadol Actifast Tablets 500mg (paracetamol)

Releases paracetamol even before it reaches the stomach.15 Does not compromise the stomach’s protective lining and can be taken even on an empty stomach or by those at risk of stomach ulcers.4,5*

Panadol Extra pack shot

Panadol Extra 500mg/65mg Soluble Effervescent Tablets (paracetamol, caffeine)

The ingredients in Panadol Extra Soluble provides fast and effective relief for tough pain.9-13

Panadol Night

Panadol Night Film-coated Tablets (paracetamol 500mg, Diphenhydramine hydrochloride 25mg)

Panadol Night relieves night time pain. The dual active formulation aids restful sleep. Exclusive to pharmacy.

Panadol Baby

Panadol Baby 120mg/5ml Oral Suspension (paracetamol)

Suitable for babies and children from 2 months to 12 years.

Made in Ireland

Made in Ireland

Panadol pain relief tablets are manufactured in Ireland.

Panadol in practice

Woman touching her forehead in pain

Headache disorders

Headache disorders, characterised by recurrent episode of headaches, are one of the most common disorders of the nervous system and, can be painful and disabling to sufferers.16 Find out more about tension-type headaches, “red flag” symptoms and how to manage them.

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Products

Find out how our tailored treatments can help your patients manage their everyday pain.

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Joint pain & osteoarthritis

Based on the 2018 Global Pain Index (GPI), 92% of 24,000 people surveyed around the world suffered from some pain and 87% experienced joint pain.17 Discover more about joint and osteoarthritic pain including signs and symptoms and, how to manage them.

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