Voltaren—Arthritis Knee Pain Relief Efficacy

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Clinically Proven to Offer Significant Pain Relief in OA of the Knee

Knee OA efficacy

Voltaren® Arthritis Pain gel OTC is clinically proven to relieve the pain of arthritis, reduce stiffness, and improve mobility1,2

Differences between Voltaren® Arthritis Pain and placebo were evident at Week 1 and were maintained through Week 12.1

This clinical trial sought out how Voltaren® Arthritis Pain gel OTC compared to placebo in improving pain and function in 492 patients with OA over 12 weeks.

Following an initial visit, patients returned for follow-up assessment for metrics based on efficacy, safety, and disease activity:

  • Voltaren® Arthritis Pain gel OTC was significantly superior to placebo for all primary efficacy outcomes at Week 12.1
  • Voltaren® Arthritis Pain gel OTC also demonstrated significant improvements in WOMAC pain, WOMAC Physical Function, and Global Rating of Disease vs placebo at Weeks 1, 4, and 8.1 
  • Patient population included overweight and obese individuals.1
  • A 12-week, randomized, double-blind, multicenter, vehicle-controlled, parallel-group study of diclofenac sodium gel 1% for the relief of signs and symptoms in 492 adults aged ≥35 years with osteoarthritis of the knee. Following the initial visit, patients returned for follow-up assessments at Weeks 1, 4, 8, and 12.1

  • WOMAC is a pain measurement index and was used to capture the data in the prior Pain and Physical Function graphs. WOMAC was calculated after patients answered 24 questions on a 0 to 4 Likert scale. Sums of responses to subsets of questions yield indices for pain (scale: 0 to 20), physical function (scale: 0 to 68), and stiffness (scale: 0 to 8). For the contralateral knee, patients answered 4 questions (abridged WOMAC), Q2 and Q4 in the pain scale, and Q14 and Q24 in the physical function scale.1

Find out more about Voltaren® Arthritis Pain

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How does Voltaren® Arthritis Pain gel OTC stack up against the competition?

Voltaren® Arthritis Pain vs oral and topical analgesics

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What about adverse events and other risks?

Voltaren® Arthritis Pain gel OTC has an established safety profile that includes NSAID class warnings.

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Emulgel penetration

What is an emulgel?

Voltaren® Arthritis Pain gel OTC has a unique formulation.

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Drug Facts

Voltaren® Arthritis Pain gel OTC Drug Facts

The drug facts contain all you need to know about dosing and administration.

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MOA molecule

How does Voltaren® Arthritis Pain gel OTC relieve pain?

The science behind Voltaren® Arthritis Pain and its MOA. 

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Treat OA

How to treat OA Pain?

The latest OA treatment guidelines from the American College of Rheumatology.

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